What Is The Major Function Of The Juxtaglomerular Apparatus?

Where is the Juxtaglomerular apparatus located quizlet?

Where is the Juxtaglomerular Apparatus located.

In the distal tubule, specifically the region that passes between the afferent & efferent arterioles.

Tubuloglomerular feedback about the sodium & chloride composition in the distal tubule affects arteriolar tone..

What is the function of the macula densa cells of the Juxtaglomerular Complex JGC quizlet?

What is the function of the macula densa cells of the juxtaglomerular complex (JGC)? The macula densa cells monitor the NaCl content of the filtrate entering the distal convoluted tubule.

What is important functionally about the specialized epithelium in the bladder quizlet?

WHAT IS IMPORTANT FUNCTIONALLY ABOUT THE SPECIALIZED EPITHELIUM (TRANSITIONAL EPITHELIUM) IN THE BLADDER? THEY HAVE ABILITY TO SLIDE OVER ONE ANOTHER, THUS DECREASING THE THICKNESS OF THE MUCOSAL LAYER AS THE BLADDER FILLS & STRETCHES TO ACCOMMODATE THE INCREASED URINE VOLUME.

What do mesangial cells secrete?

Mesangial cells are also specialized cells and have many important functions. They secrete an extracellular matrix substance (mesangial matrix) rich in laminin and fibronectin that helps support the capillary tuft. Some mesangial cells contain actomyosin filaments and are contractile.

Why is urine concentrated?

The laboratory will test how concentrated your urine is. More concentrated urine means that there are more solutes and less water in the sample. Solutes are dissolved particles, such as sugars, salts, and proteins. Normal values may vary based on the laboratory used.

What is the function of the Juxtaglomerular apparatus quizlet?

Macula Densa & Juxtaglomerular cells. What is the main function of the Juxtaglomerular apparatus? To secrete Erythropoitein and Renin.

What does the Juxtaglomerular apparatus produce?

The juxtaglomerular apparatus (see Fig. 1.5) comprises the macula densa, the extraglomerular mesangium, the terminal portion of the afferent arteriole with its renin-producing granular cells (nowadays also often termed juxtaglomerular cells), and the beginning portions of the efferent arteriole.

What is the Juxtaglomerular complex quizlet?

juxtaglomerular complex….where most distal portion of ascending limb of nephron loop lies against afferent arteriole. macula densa. tall, closely packed cells; contain chemoreceptors that monitor NaCl content in DCT.

What activates Juxtaglomerular cells?

Juxtaglomerular Cells Although they are activated by prostaglandins released from the macula densa cells, they can also release renin independently of the macula densa. Baroreceptors found in the arterioles trigger renin secretion if there is a fall in blood pressure in the arterioles.

What is the chief force pushing water and solutes?

Glomerular hydrostatic pressure (HPg), which is essentially glomerular blood pressure, is the chief force pushing water and solutes out of the blood and across the filtration membrane.

Where is urine most dilute?

medullaThe region of the kidney that is responsible for the generation of concentrated or dilute urine is the medulla (figure 1).

How do you make urine concentrate?

It is now generally agreed that the formation of concentrated urine in the mammalian kidney is effected by the production of a highly concentrated environment around the medullary collecting ducts in which the final concentrating process occurs by osmotic equilibration of the collecting duct contents with the …

What stimulates macula densa cells?

The cells of the macula densa are sensitive to the concentration of sodium chloride in the distal convoluted tubule. … As such, an increase in sodium chloride concentration would result in vasoconstriction of afferent arterioles, and reduced paracrine stimulation of juxtaglomerular cells.

What do macula densa cells secrete?

Macula densa cells in the distal nephron, according to the classic paradigm, are salt sensors that generate paracrine chemical signals in the juxtaglomerular apparatus to control vital kidney functions, including renal blood flow, glomerular filtration, and renin release.

What are Juxtaglomerular cells?

The juxtaglomerular cells (JG cells, or granular cells) are cells in the kidney that synthesize, store, and secrete the enzyme renin. They are specialized smooth muscle cells mainly in the walls of the afferent arterioles (and some in the efferent arterioles) that deliver blood to the glomerulus.

Which structure is most important for urine concentration?

Which structure is most important for urine concentration? Capsular hydrostatic pressure is the chief force pushing water and solutes out of the blood and across the filtration membrane.

What is the significance of JGA in kidney function?

The juxtaglomerular apparatus is part of the kidney nephron, next to the glomerulus. It is found between afferent arteriole and the distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate.

What enzyme is released by the Juxtaglomerular complex to regulate GFR?

ReninRenin is an enzyme that is produced by the granular cells of the afferent arteriole at the juxtaglomerular apparatus.