Can FNA Results Be Wrong?

Why FNAC is done for thyroid?

FNAC is widely accepted as the most accurate, sensitive, specific, and cost-effective diagnostic procedure in the preoperative assessment of thyroid nodules.

The accuracy of the FNAC analysis approaches 95% in the differentiation of the benign nodules from the malignant nodules of the thyroid gland..

How long does it take to get FNA biopsy results?

A result can often be given within 2 to 3 days after the biopsy. A result that requires a more complicated analysis can take 7 to 10 days. Ask your doctor how you will receive the biopsy results and who will explain them to you.

What does it mean when a thyroid biopsy comes back suspicious?

“Suspicious” thyroid biopsy: this happens usually when the diagnosis is a follicular or hurtle cell caused lesion. Follicular and hurtle cells are normal cells found in the thyroid. Current analysis of thyroid biopsy results cannot differentiate between follicular or hurtle cell cancer from noncancerous adenomas.

Can a fine needle biopsy be wrong?

In general, needle biopsies have a higher risk of a false negative result than a surgical biopsy. Needle biopsies take a smaller tissue sample and may miss the cancer. However, even with needle biopsies, false negative results are not common.

How accurate is FNAC test?

FNAC achieved a sensitivity of 92.8, a specificity of 94.2%, a positive predictive value of 94.9%, a negative predictive value of 91.8%, a false positive rate of 7.2%, a false negative rate of 5.8%, and a total accuracy of 93.6%.

Are biopsies 100 accurate?

Of the adequate specimens, the accuracy of core/open/fine needle biopsy was 96%, 97% and 94% for determining malignant versus benign; of the correctly identified malignant lesions 97%, 100% and 80% were accurate for histological grade; and 79%, 84%, 59% for histological subtype.

What happens if FNAC test is positive?

When FNAC shows a positive finding, treatment should be given accordingly as FNAC has a high PPV. However, when FNAC shows a negative result, malignancy cannot be reliably ruled out since the NPV of FNAC is low (37%). PET/CT is then performed in these patients.

How long does it take for FNAC report?

When Will I Get My Results? Generally, your results should be available from your surgeon’s office in two to three working days. The results can be grouped into three categories: Clearly benign – not cancer.

How long do FNA results take?

HOW LONG DOES IT TAKE FOR THE RESULTS TO RETURN? Generally, it can take anywhere from a few days to two (2) weeks for the result to return.

How accurate is Fna?

Fine-needle aspiration biopsy (FNAB) is an efficient and reliable means for the evaluation of thyroid nodules, and it has been shown to have a diagnostic sensitivity of 89% to 98% and a specificity of 92%.

Can a thyroid biopsy be wrong?

Although most of the time the thyroid biopsy provides an accurate diagnosis, sometimes the results can be inconclusive. Also, rarely a biopsy result may be incorrect and be read as cancerous when no cancer is present or read as benign when a cancer actually is present.

Is it possible for a biopsy to be wrong?

Although tests aren’t 100% accurate all the time, receiving a wrong answer from a cancer biopsy – called a false positive or a false negative – can be especially distressing. While data are limited, an incorrect biopsy result generally is thought to occur in 1 to 2% of surgical pathology cases.